Web12 Apr 2024 · Lin et al. found that circ_0021155 was upregulated in ox-LDL-treated human aorta vascular smooth muscle cells (HASMCs), and overexpression of circ_0021155 promoted HASMC proliferation and migration with a decrease in the protein levels of α-actin, calponin, and smooth muscle myosin heavy chain (SMMHC) as well as an increase in … Web1 Jan 2024 · Smooth muscle cell phenotypic diversity. Arterioscler Thromb Vasc Biol, 39 (2024), pp. 1715-1723. CrossRef View in Scopus Google Scholar. 3. ... Atheroprotective roles of smooth muscle cell phenotypic modulation and the TCF21 disease gene as revealed by single-cell analysis.
Potential of PCSK9 as a new target for the management of LDL …
Web15 Jan 2016 · Regulation and characteristics of vascular smooth muscle cell phenotypic diversity. Neth Heart J 2007;15(3):100–8. pmid:17612668 . View Article PubMed/NCBI … Web5 Jun 2024 · Vascular smooth muscle cells (VSMC) are stromal cells of the blood vessels and their differentiation is thought to be essential during atherosclerosis. Cathelicidin-related antimicrobial peptides (CRAMP) are suggested to play a role in the development of atherosclerosis. Even so, the relationship of CRAMP and VSMC remains unclear. The … fairweather lodge san antonio texas
Potential of PCSK9 as a new target for the management of LDL …
Web23 hours ago · Smooth Muscle Cell Phenotypic Diversity. [Role of intercellular communications in hepatic differentiation and carcinogenesis]. KLF4 Dependent Phenotypic Modulation of SMCs Plays a Key Role inAtherosclerotic Plaque Pathogenesis; Phenotypic changes to vascular smooth muscle cells induced by oxidant-modified extracellular matrix Web20 Nov 2024 · A common event in CVD pathophysiology is the switch of vascular smooth muscle cells (VSMCs) from a contractile to a synthetic phenotype. Interestingly, oxidative stress is a major contributor to this phenotypic switch. ... Van Eys, G. Regulation and characteristics of vascular smooth muscle cell phenotypic diversity. Neth. Heart J. 2007, … Web12 hours ago · Using single-cell RNA sequencing, researchers identified 12 atherosclerosis-associated cell states and found that Vcam1+ smooth muscle cell state contributed the most to the genetic heritability of coronary artery disease. A hybrid polygenic risk score (PRS) that considers cell-type-specific regulatory elements demonstrated improved … fairweather lodge iowa city iowa